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2024

 

161. Wei-Hsiang Ma,# Che-Chia Chang,# Te-Sheng Lin,* Yu-Chie Chen* Distinguishing Methicillin-resistant Staphylococcus aureus from Methicillin-sensitive Strains by Combining Fe3O4 Magnetic Nanoparticle-based Affinity Mass Spectrometry with A Machine Learning Strategy. Microchimica Acta, 2024, accepted (#equal contribution to this work).

160. Miftakhul Jannatin, Tzu-Ling Yang, Yi-Yuan Su, Ru-Tsun Mai, Yu-Chie Chen* Europium ion-based magnetic trapping and fluorescence-sensing method for detection of pathogenic bacteria. Anal. Chem. https://doi.org/10.1021/acs.analchem.4c00655

159. Suchita Paul, Sandeep Verma* and Yu-Chie Chen* Peptide dendrimer-based antibacterial agents: synthesis and applications. ACS Infect. Dis. 2024. https://doi.org/10.1021/acsinfecdis.3c00624.

 158. Chi-Feng Tu and Yu-Chie Chen* Utilizing a metal inlet coiled with copper wire as the ion source for ambient ionization mass spectrometry. Anal. Chem. 2024, 96, 661–667.

 157. Chih-Wei Chen, Tzu-Ling Yang, Yu-Chie Chen *Using magnetic micelles combined with carbon fiber ionization mass spectrometry for screening of trace triazine herbicides from aqueous samples. Molecules. 2024, 29, 137.

156. Cheng-Hsin Chiu, De-Yi Huang, Wei-Hsiang Ma, Yu-Xun Chen, Sih-Yu Yang, Yu-Chie Chen*, Kwok-Kong Tony Mong* Chemical approach for investigation of the structure-activity relationship of salmycin and identification of a glycan-based analogue for drug resistant Staphylococcus aureus. Adv. Synth. Catal. 2024, 366, 101-113.

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2023

155. Jia-Jen Tsai,# Che-Chia Chang,# De-Yi Huang, Te-Sheng Lin*, and Yu-Chie Chen* Analysis and classification of coffee beans using single coffee bean mass spectrometry with machine  learning strategy. Food Chemistry, 2023, 426, 136610 (# The authors contributed equally to this work).

154. Yan-Cen Zhan, Chin-Poa Chiu, Yu-Chie Chen*, Using lanthanide ions as magnetic and sensing probes for the detection of tetracycline from complex samples. J. Food Drug Anal. 2023, 5, 371-380.
153. Chih-Wei Chen, Tzu-Ling Yang, and Yu-Chie Chen* Using magnetic micelles as adsorbents to remove dyes from aqueous solutions. J. Environ. Chem. Eng. 2023, 11, 109457.

152. Jia-Jen Tsai, Yan-Cen Zhan, Yi-Ying Wu, Yu-Chie Chen* A facile switch-on fluorescence sensing method for detecting phosphates from complex aqueous samples, Sens. Actuators B Chem. 2023, 380, 133298.

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2022

151. Yan-Cen Zhan, Jia-Jen Tsai, and Yu-Chie Chen* Zinc Ion-based switch-on fluorescence-sensing probes for the detection of tetracycline. Molecules. 2022, 27, 8403.

150. Jia-Jen Tsai, Yu-Ting Lai, and Yu-Chie Chen* Using Solid-Phase Microextraction Coupled with Reactive Carbon Fiber Ionization-Mass Spectrometry for the Detection of Aflatoxin B1 from Complex Samples. Separations. 2022, 9(8), 199.

149. Karuppuchamy Selvaprakash, Yu‑Chie Chen* Using an insulating fiber as the sampling probe and ionization substrate for ambient ionization–mass spectrometric analysis of volatile, semi‑volatile, and polar analytes. Anal. Bioanal. Chem. 2022, 414, 4633–4643.

148. De-Yi Huang, Jia-Jen Tsai, Yu-Chie Chen* Direct mass spectrometric analysis of semivolatiles derived from real samples at atmospheric pressure. ACS. Omega, 2022, 7, 12, 10255–10261.

147. Juli Novita Sari, Karthikeyan Kandasamy, Yu-Chie Chen* Detection of Escherichia coli by Combining an Affinity-Based Method with Contactless Atmospheric Pressure Ionization Mass Spectrometry. Separations. 2022, 9,13.

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2021

146. De-Yi Huang, Meng-Jiy Wang, Jih-Jen Wu, Yu-Chie Chen. Ionization of Volatile Organics and Nonvolatile Biomolecules Directly from a Titanium Slab for Mass Spectrometric Analysis. Molecules, 2021, 26, 6760.

145. Karthikeyan Kandasamy, Miftakhul Jannatin, Yu-Chie Chen* Rapid detection of pathogenic bacteria by the naked eye. Biosensors. 2021, 11, 317.

144. Karthikeyan Kandasamy, Karuppuchamy Selvaprakash, Yu-Chie Chen* Functional magnetic nanoparticle-based affinity probe for MALDI mass spectrometric detection of ricin B. Microchimica Acta, 2021, 12;188, 339.

143. Yu-Ting Lai,# Karthikeyan Kandasamy,# and Yu-Chie Chen* Magnetic Graphene Oxide-Based Affinity Surface-Assisted Laser Desorption/Ionization Mass Spectrometry for Screening of Aflatoxin B1 from Complex Samples. Anal. Chem. 2021, 93, 7310-7316 (# The authors contributed equally to this work).

142. Yen-Chun Chen, Arun Krishnamurthy, Szu-Hua Chen, Yu-Chie Chen*A Tapered Capillary-based Contactless Atmospheric Pressure Ionization Mass spectrometry for On-line Preconcentration and Separation of Small Organics. Separations, 2021, 8, 111.

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2020

141. Karuppuchamy Selvaprakash, Yu-Chie Chen* Glycosylated protein-functionalized gold nanoparticle-based detection of heat-labile enterotoxin from complex samples. Sensor Actuat. B-Chem. 2020, 322, 128640.

140. Jia-Lin Wu, De-Yi Huang, and Yu-Chie Chen* Using gadolinium ions as affinity probes to selectively enrich and magnetically isolate bacteria from complex samples. Anal. Chim. Acta. 2020, 29, 18–25.

139. Yi-Cheng Wu and Yu-Chie Chen* Reactive carbon fiber ionization mass spectrometry for characterization of unsaturated hydrocarbons from plant aroma. Anal. Bioanal. Chem. 2020, 412, 5489–5497.

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2019

138. Min-Li Wu,& Te-Yu Chen,& Wen-Jie Chen, Mirza Muhammad Fahad Baig, Yi-Cheng Wu, Yu-Chie Chen* Carbon fiber ionization mass spectrometry coupled with solid phase microextraction for analysis of benzo[a]-pyrene. Anal. Chim. Acta. 2019. 1049, 133–140 (& the authors contributed equally to this work).

137. Te-Yu Chen, Min-Li Wu, Yu-Chie Chen* Ultrasonication-assisted spray ionization-based micro-reactors for on-line monitoring of fast chemical reactions by mass spectrometry. J. Mass Spectrom. 2019, 54, 26–34.

136. Ching-Yi Wu and Yu-Chie Chen* Riboflavin Immobilized Fe3O4 magnetic nanoparticles carried with n-butylidenephthalide as targeting-based anticancer agents. Artif. Cells Nanomed. Biotechnol. 2019, 47, 210–220.

135. Min-Li Wu, Yi-Cheng Wu, and Yu-Chie Chen* Detection of pesticide residues on intact tomatoes by carbon fiber ionization mass spectrometry. Anal. Bioanal Chem. 2019, 411, 1095–1105.

134. Mirza Muhammad Fahad Baig, Yu-Chie Chen* Gold nanocluster-based fluorescence sensing probe for detection of dipicolinic acid. Analyst. 2019,144, 3289–3296.

133. Wen-Jie Chen, Karthikeyan Kandasamy, Yu-Chie Chen* Functional gold nanoparticles as sensing probes for concanavalin A and as imaging agents for cancer cells. ACS Appl. Nano Mater. 2019, 2, 6, 3348-3357.

132. Yi-Ling Bai, Md. Shahed-Al-ahmud, Karuppuchamy Selvaprakash, Nien-Tsung Lin*, Yu-Chie Chen* Tail Fiber Protein-Immobilized Magnetic Nanoparticle-Based Affinity Approaches for Detection of Acinetobacter baumannii. Anal. Chem. 2019, 91, 15, 10335-10342.

131. Karthikeyan Kandasamy, Karuppuchamy Selvaprakash, Yu-Chie Chen* Using lactosylated cysteine functionalized gold nanoparticles as colorimetric sensing probes for rapid detection of the ricin B chain. Microchimica Acta, 2019, 186, 847.
 

2018

130. Karuppuchamy Selvaprakash, Yu-Chie Chen* Functionalized gold nanoparticles as affinity nanoprobes for multiple lectins. Colloids Surf. B Biointerfaces. 2018,162, 60-68.

129. Mirza Muhammad Baig,Yu-Chie Chen* Gold nanoparticle-based colorimetric sensing of dipicolinic acid from complex samples. Anal. Bioanal. Chem. 2018, 410, 1805-1815.

128. Chun-Hsien Li, Yi-Ling Bai, Yu-Chie Chen* Inhibition of the lethality of Shiga-like toxin-1 by functional gold nanoparticles. Artif. Cells Nanomed. Biotechnol. 2018, 46(sup1), 841-851.

127. Ching-Yi Wu, Min-Li Wu, Yu-Chie Chen* Selective extraction of n-butylidenephthalide from Angelica sinensis (Danggui) by using functionalized iron oxide magnetic nanoparticles as trapping probes. Anal. Methods. 2018, 2018,10, 1593-1601.

126. Sin-Ge Wang,& Yen-Chun Chen,& Yu-Chie Chen* Antibacterial gold nanoparticle-based photothermal killing of vancomycin-resistant bacteria. Nanomedicine, 2018, 13, 1405-1416 (&contributed equally to this work).

125. Jia-Lin Wei and Yu-Chie Chen* Using magnetic ions to probe and induce magnetism of pyrophosphates, bacteria, and mammalian cells.  ACS Appl. Mater. Inter. 2018,10, 30837–30843.

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2017

124. Min-Li Wu,& Te-Yu Chen,& Yen-Chun Chen, Yu-Chie Chen* Carbon fiber iIonization mass spectrometry for the analysis of analytes in vapor, liquid, and solid phases. Anal. Chem, 2017, 89, 13458–13465 (& contributed equally to this work).

123. Karuppuchamy Selvaprakash, Yu-Chie Chen* Detection of ricin by using gold nanoclusters functionalized with chicken egg white proteins as sensing probes.  Biosens. Bioelectron. 2017, 92, 410–416.

122. Anil Kumar Meher, Yu-Chie Chen* Electrospray modifications for advancing mass spectrometric analysis, Mass Spectrometry, 2017, 6, S0057-S0057.

121. Anil  Kumar Meher, Yu-Chie Chen* Analysis of volatile compounds by open-air ionization mass spectrometry. Anal. Chim. Acta. 2017, 966, 41–46.

120. Mirza Muhammad Fahad Baig, Yu-Chie Chen* Bright carbon dots as fluorescence sensing agents for bacteria and curcumin. J. Colloid Interface Sci. 2017, 501, 341-349.  

119. Chun-Hsien Li, Yi-Ling Bai, Karuppuchamy Selvaprakash, Kwok-Kong Tony Mong, Yu-Chie Chen* Selective detection of Shiga-like toxin 1 from complex samples using pigeon ovalbumin functionalized gold nanoparticles as affinity probes. J. Argic Food Chem., 2017, 65, 4359-4365.

118. Kai-Chieh Lee, Wen-Jie Chen, Yu-Chie Chen* Using dextran-encapsulated gold nanoparticles as insulin carriers to prolong insulin activity. Nanomedicine, 2017, 12, 1823-1834.

117. Yet-Ran Chen, Yu-Chie Chen, Yu-Ju Chen, Pao-Chi Liao, Jentaie Shiea,* Pawel L. Urban,* Yi-Sheng Wang* A Role Model with Endless Enthusiasm for Science: In Memory of Tsutomu Masujima. J. Mass Spectrom. Soc. Japan, 2017, 65, 150-153.

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2016

116.  Fang-Yin Kuo, Wei-Lien Lin and Yu-Chie Chen*Affinity Capture Using Peptide-functionalized Magnetic Nanoparticles to Target Staphylococcus aureus. Nanoscale. 2016, 8, 9217-9225.

115. Mirza Muhammad Fahad Baig, Cheng-Tai Chen, Yu-Chie Chen* Photoluminescence Determination of Aluminum Using Glutathione-capped Gold Nanoclusters. Anal. Lett. 2016, 49, 2246-2258.

114.Ya-Ru Tang, Hsin-Yi Huang, Jie-Bi Hu, Rajesh Rattinam, Chun-Hsien Lee, Yu-Chie Chen, Pawel Urban* Capillary Hydrodynamic Chromatography Reveals Temporal Profiles of Cell Aggregates. Anal. Chim. Acta. 2016, 910, 75–83.

113. Kai-Chieh Lee,& Hsiang-Ling Chiang,& Wei-Ru Chiu, Yu-Chie Chen* Molecular Recognition between Insulin and Dextran Encapsulated Gold Nanoparticles. J. Mol. Recognit. 2016, 29, 528-535 (& contributed equally to this work).

112. Ching-Yi Wu, Kai-Chieh Lee, Yen-Ling Kuo, Yu-Chie Chen* Revisiting the quantitative features of surface-assisted laser desorption/ionization mass spectrometric analysis. Philos Trans A Math Phys Eng Sci. 2016, 2079, 374.

111. Ssu-Ying Chen, Ching-Yi Wu, Yu-Chie Chen, and Pawel L. Urban* One-Step Detection of Major Lipid Components in Submicroliter Volumes of Unpurified Liposome and Cell Suspensions. Anal. Chem., 2016, 88, pp 7337–7343.

110. Anil Kumar Meher, Yu-Chie Chen* Online Monitoring of Chemical Reactions by Polarization-induced Electrospray Ionization. Anal. Chim. Acta. 2016, 937, 106–112.

109. Yen-Ling Kuo, Sin-Ge Wang, Ching-Yi Wu, Kai-Chieh Lee, Chan-Jung Jao, Shiu-Huey Chou, Yu-Chie Chen* Functional Gold Nanoparticle-based Antibacterial Agents for Nosocomial and Antibiotic-resistant Bacteria. Nanomedicine, 2016, 11, 2497-2510.

108. Anil Kumar Meher, Yu-Chie Chen* Combination of Raman Spectroscopy and Mass Spectrometry for Online Chemical Analysis. Anal. Chem. 2016, 88, 9151-9157.

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2015

107. Anil Kumar Meher, Yu-Chie Chen* Polarization induced electrospray ionization mass spectrometry for the analysis of liquid, viscous, and solid samples. J. Mass Spectrom. 2015, 50, 444-450.

106.  Hong-Zheng Lai, Wei-Yu Chen, Ching-Yi Wu, Yu-Chie Chen* Potent antibacterial nanoparticles for pathogenic bacteria. ACS Appl. Mater. Inter. 2015, 7, 2046-2054.

105. Jie-Bi Hu, Ting-Ru Chen, Yu-Chie Chen, and Pawel L. Urban* Microcontroller-Assisted Compensation of Adenosine Triphosphate Levels: Instrument and Method Development. Sci. Rep. 2015, 5, 8135.

104. Jie-Bi Hu, Ting-Ru Chen, Chia-Hsien Chang, Ji-Yen Cheng, Yu-Chie Chen, Pawel L Urban* Compact 3D-Printed Interface for Coupling Open Digital Microchips with Venturi  Easy Ambient Sonic-Spray Ionization Mass Spectrometry. Analyst 2015, 140,1495-501.

103. Hong-Zheng Lai, Sin-Ge Wang, Ching-Yi Wu, Yu-Chie Chen* Detection of Staphylococcus aureus by functional gold nanoparticle-based affinity surface-assisted laser desorption/ionization mass spectrometry. Anal. Chem. 2015, 87, 2114-2120.
102. Ching-Yi Wu, Chia-Hua Lin, Yu-Chie Chen* Using Glucose-bound Fe3O4 Magnetic Nanoparticles as Photothermal Agents for Targeted Hyperthermia of Cancer Cells. J. Nanomed. & Nanotechnolog. 2015, 6, 1000264.  

101. Fang-Yin Kuo, Bo Yao Chang, Ching-Yi Wu, Kwok-Kong Tony Mong,* Yu-Chie Chen* Magnetic Nanoparticle-based Platform for Rapid Characterization of Shiga-like Toxin 1 from Complex Samples. Anal. Chem. 2015, 87, 10513–10520.

100. Anil Kumar Meher and Yu-Chie Chen* Tissue paper assisted spray ionization mass spectrometry. RSC Adv. 2015, 5, 94315-94320.

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2014

99. Shu-Hsuan Lin, Ta-Ju Lo, Fang-Yin Kuo, Yu-Chie Chen* Real time monitoring of accelerated chemical reactions by ultrasonication-assisted spray ionization mass spectrometry. J. Mass Spectrom. 2014, 49, 50–56.

98. Jie-Bi Hu, Ssu-Ying Chen, June-Tai Wu, Yu-Chie Chen,* Pawel L. Urban* Automated System for Extraction and Instantaneous Analysis of Millimeter-Sized Samples. RSC. Adv. 2014, 4, 10693-10701.

97. Chia-Hsien Chang, Tsung-Yi Chen, Yu-Chie Chen* Microfluidic Chip Coupled with Thermal Desorption Atmospheric Pressure Ionization Mass Spectrometry. Mass Spectrometry (Tokyo), 2014, DOI: 10.5702/massspectrometry. S0026.

96. Song-Yi Wong and Yu-Chie Chen* Droplet-based Electrospray Ionization Mass Spectrometry for Qualitative and Quantitative Analysis. J. Mass Spectrom. 2014, 49, 432–436.

95. Chen-Wei Li, Kai-Wei Hon, Bhaswati Ghosh, Po-Han Li, Po-Han Chan, Hsien-Ya Lin, Chun-Hung Lin, Yu-Chie Chen,* and Kwok-Kong Tony Mong*  Synthesis of Oligomeric Mannosides and Their Structure-binding Relationship with Concanavalin A. Chem-Asian J., 2014, 9, 1786-1796.

94. Karuppuchamy Selvaprakash and Yu-Chie Chen* Using Protein-Encapsulated Gold Nanoclusters as Photoluminescent Sensing Probes for Biomolecules. Biosens. Bioelectron. 2014, 61, 88-94.

93. Wei-Ju Chiu, Wei-Yu Chen, Hong-Zheng Lai, Ching-Yi Wu, Hsiang-Lin Chiang, Yu-Chie Chen* Dextran-encapsulated Photoluminescent Gold Nanoclusters: Synthesis and Application. J. Nanopart. Res. 2014,16, 2478.

92. Jie-Bi Hu, Sampath Gunathilake, Yu-Chie Chen, Pawel L. Urban.* On the Dynamics of Kefir Volatome. RSC Adv. 2014, 4, 28865-28870.

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2013

91. Yu-Chie Chen and Pawel L. Urban* Time-Resolved Mass Spectrometry. TRAC-Trend Anal. Chem. 2013, 44, 106-120.

90. Jie-Bi Hu, Yu-Chie Chen*, Pawel L. Urban* Coffee-Ring Effects in Laser Desorption/Ionization Mass Spectrometry. Anal. Chim. Acta. 2013, 766, 77–82.

89. Jonathan Fang and Yu-Chie Chen* Nanomaterials for Photohyperthermia: A Review. Curr. Pharm. Des. 2013,19, 6622-6634.

88.  Po-Han Chan, Bhaswati Ghosh, Hong-Zheng Lai, Hwei-Ling Peng, Kwok Kong Tony Mong,* Yu-Chie Chen* Photoluminescent Gold Nanoclusters as Sensing Probes for Uropathogenic Escherichia coli. PLoS One. 2013, e58064.

87. Shin-Yi Huang, Yu-Chie Chen* Magnetic Nanoparticle-based Platform for Rapid Characterization of Histidine-rich Proteins and Peptides Anal. Chem. 2013, 85, 3347-3354.

86. Po-Han Li, Shin-Yi Huang, Yu-Chie Chen,* Pawel L. Urban* A Hybrid Nanoparticle Matrix for Mass Spectrometry. RSC Adv. 2013, 3, 6865–6870.

85. Cheng-Huan Hsieh, Anil Kumar Meher, Yu-Chie Chen* Automatic Sampling and Analysis of Organics and Biomolecules by Capillary Action-Supported Contactless Atmospheric Pressure Ionization Mass Spectrometry. PLoS One, 2013, 8, e66292.

84. Po-Han Chan, Song-Yi Wong, Shu-Hsuan Lin, Yu-Chie Chen* Lysozyme-encapsulated Gold Nanocluster-based Affinity Mass Spectrometry for Pathogenic Bacteria. Rapid Commun. Mass Spectrom. 2013, 27, 2143-2148.

83. Hsin-Yi Huang, Ta-Ju Lo, Yu-Chie Chen,* Jie-Bi Hu, Pawel L. Urban* Liquid-Phase and Gas-Phase Investigation of Biomolecules in a Single Experiment. Anal. Meth. 2013, 5, 5908-5911. 

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2012

82. Ta-Ju Lo, Tsung-Yi Chen, Yu-Chie Chen* Study of salt effects in ultrasonication-assisted spray ionization mass spectrometry. J. Mass Spectrom. 2012, 47, 480-483.

81. Cheng-Huan Hsieh, Chin-Sheng Chao, Kwok-Kong Tony Mong, Yu-Chie Chen* Online monitoring of chemical reactions by contactless atmospheric pressure ionization mass spectrometry. J. Mass Spectrom. 2012, 47, 586-590.

80. Jie-Bi Hu, Yu-Chie Chen,* Pawel L. Urban* On-target labeling of intracellular metabolites combined with chemical mapping of individual hyphae revealing cytoplasmic relocation of isotopologues. Anal. Chem. 2012, 84, 5110–5116.

79. Po-Han Li, Ju-Yu Lin, Cheng-Tai Chen, Wei-Ru Ciou, Po-Han Chan, Liyang Luo, Hung-Yu Hsu, Eric Wei-Guang Diau, Yu-Chie Chen* Using Gold Nanoclusters as Selective Luminescent Probes for Phosphate-containing Metabolites. Anal. Chem. 2012, 84, 5484–5488.

78. Po-Han Chan and Yu-Chie Chen,* Human Serum Albumin Stabilized Gold Nanoclusters as Selective Luminescent Probes for Staphylococcus aureus and Methicillin-Resistant   Staphylococcus aureus. Anal Chem. 2012, 84, 8952-8956.

77. Te-Wei Tseng, June-Tai Wu, Yu-Chie Chen,* Pawel L. Urban* Isotope  Label-aided Mass Spectrometry Reveals the Influence of Environmental Factors on Metabolism in Single Eggs of Fruit Fly. PLoS One. 2012, 7, e50258.

76. Po-Han Li, Hsu Ting, Yu-Chie Chen, Pawel L. Urban* Recording Temporal Characteristics of Convection Currents by Continuous and Segmented-Flow Sampling. RSC Adv. 2012, 2, 12431-12437.

75. Ta-Ju Lo, Chia-Hsien Chang, Yu-Chie Chen* Syringe Infusion-based Contactless Atmospheric Pressure Ionization Mass Spectrometry for Small and Large Biomolecules. Mass Spectrom. Lett. 2012, 3, 87-92.

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2011

74. Jen-Yi Chen, Kar-Wei Hon, Yu-Chie Chen* Multilayer Gold Nanoparticle-Assisted Protein Tryptic Digestion in Solution and in Gel under Photothermal Heating. Anal. Bioanal. Chem. 2011, 399, 377-385.

73. Jen-Yi Chen and Yu-Chie Chen*A Label-Free Sensing Method for Phosphopeptides Using Two-layer Gold Nanoparticle-based Localized Surface Plasma Resonance Spectroscopy. Anal. Bioanal. Chem. 2011, 399, 1173-1180.

72. Tsai-Jung Yu, Po-Han Li, Te-Wei Tseng, Yu-Chie Chen* Multifunctional Fe3O4/alumina Core/Shell Magnetic Nanoparticles as Photothermal Agents for Targeted Hyperthermia of Nosocomial and Antibiotic-resistant Bacteria. Nanomedicine, 2011, 6, 1353-3163.

71. Cheng-Huan Hsieh, Chia-Hsien Chang, Pawel L. Urban, and Yu-Chie Chen* Capillary Action-supported Contactless Atmospheric Pressure Ionization for the Combined Sampling and Mass Spectrometric Analysis of Biomolecules. Anal. Chem. 2011, 83, 2866–2869.

70. Pawel L. Urban, Chia-Hsien Chang, June-Tai Wu, Yu-Chie Chen* Microscale MALDI Imaging of Outer-Layer Lipids in Intact Egg Chambers from Drosophila melanogaster. Anal. Chem. 2011, 83, 3918–3925.

69. Ju-Yu Lin and Yu-Chie Chen* Functional Magnetic Nanoparticle-based Trapping and Sensing Approaches for Label-Free Fluorescence Detection of DNA. Talanta. 2011, 86, 200-207.

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2010

68. Wei-Jen Chen and Yu-Chie Chen* Fe3O4@TiO2 Magnetic Nanoparticle-Based Photokilling of Pathogenic Bacteria. Nanomedicine, 2010, 5, 1585-1593.

67. Tsung-Yi Chen, Jia-Yi Lin, Jen-Yi Chen, Yu-Chie Chen* Ultrasonication-Assisted Spray Ionization Mass Spectrometry for the Analysis of Biomolecules in Solution. J. Am. Soc. Mass Spectrom. 2010, 21, 1547–1553.

66. Chih-Hau Chen, Wei-Yu Chen, Yu-Chie Chen, Ming-Juan Lee, Chyuan-Der Huang, Kaushik Chanda, and Chung-Ming Sun* Convergent Solution Phase Synthesis of Chimeric Oligonucleotides by a 2+2 and 3+3 Phosphoramidite Strategy. Aust. J. Chem. 2010, 63, 227-235.

65. Cheng-Tai Chen, Yu-Chie Chen* Functional Magnetic Nanoparticle-Based Label Free Fluorescence Detection of Phosphorylated Species. Chem. Commun. 2010, 46, 5674 - 5676.

64. Wei-Yu Chen, Ju-Yu Lin, Wei-Jen Chen,  Liyang Lo, Eric Wei-Guang Diau, Yu-Chie Chen*  Functional Gold Nanoclusters as Antimicrobial Agents for Antibiotic-resistant Bacteria. Nanomedicine, 2010, 5, 755-764.

63. Jia-Yi Lin, Tsung-Yi Chen, Jen-Yi Chen, Yu-Chie Chen* Multilayer gold nanoparticle-assisted thermal desorption ambient mass spectrometry for the analysis of small organics. Analyst. 2010, 135, 2668-2675.

62. Wei-Yu Chen and Yu-Chie Chen* Functional Fe3O4@ZnO Magnetic Nanoparticle-assisted Enrichment and Enzymatic Digestion of Phosphoproteins from Saliva. Anal. Bioanal. Chem. 2010, 398, 2049–2057.

61. Tsung-Yi Chen, Chin-Sheng Chao, Kwok-Kong Tony Mong,* Yu-Chie Chen* Ultrasonication-assisted Spray Ionization Mass Spectrometry for On-line Monitoring of Organic Reactions. Chem. Commun. 2010, 46, 8347-8349.

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2009

60.  Wei-Chieh Huang, Pei-Jane Tsai, Yu-Chie Chen*  Using multifunctional Fe3O4@Au nanoeggs as photothermal agents for selective killing of nosocomial and antibiotic-resistant bacteria. Small, 2009, 5, 51-56.

59. Hong-Yi Lin, Wei-Yu Chen and Yu-Chie Chen* Iron oxide/niobium oxide core–shell magnetic nanoparticle-based phosphopeptide enrichment from biological samples for MALDI MS analysis. J. Biomed. Nanotechnol. 2009, 5, 215-223.

58. Sheng-Yuan Chen, Rai-Long Cheng, Cheng-Kuo Tseng, Ya-Shiuan Lin, Li-Hsiang Lai, Rajesh Kumar Venkatachalam, Yu-Chie Chen, Chien-Hong Cheng and Shih-Ching Chuang* Fullerene Derivatives Incorporating Phosphoramidous Ylide and Phosphoramidate: Synthesis and Property. J. Org. Chem. 2009, 74, 4866-4869.

57. Hong-Yi Lin, Wei-Yu Chen, and Yu-Chie Chen* Iron Oxide/Tantalum Oxide Core–Shell Magnetic Nanoparticle-Based Microwave-Assisted Extraction for Phosphopeptide Enrichment from Complex Samples for MALDI MS Analysis. Anal Bioanal. Chem. 2009, 394, 2129-2136.

5. Jr-Chi Liu, Wei-Jen Chen, Chen-Wei Li, Kwok-Kong Tony Mong, Pei-Jane Tsai, Te-Lung Tsai, Yuan C. Lee, Yu-Chie Chen*

56. Identification of Pseudomonas aeruginosa using functional magnetic nanoparticle-based affinity capture combined with MALDI MS analysis. Analyst. 2009, 134, 2087 - 2094.

55. Chi-Lap Kuong, Tsai-Jung Yu, Yu-Chie Chen* Microwave-Assisted Sensing of Tetracycline Using Europium-Sensitized Luminescence Fibers as Probes. Anal Bioanal. Chem. 2009, 395, 1433-1439.

54. Cheng-Tai Chen, Wei-Jen Chen, Chao-Zong Liu, Ling-Ya Chang, Yu-Chie Chen* Glutathione-Bound Gold Nanoclusters for Selective-Binding and Detection of Glutathione S-Transferase-Fusion Proteins from Cell Lysates. Chem. Commun. 2009, 7515-7517.

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2008

53. Yu-Chih Chiu and Yu-Chie Chen* Carboxylate-Functionalized Iron Oxide Nanoparticles in Surface-Assisted Laser Desorption/Ionization Mass Spectrometry for the Analysis of Small Biomolecules. Anal. Lett. 2008, 41, 260-267.

52. Cheng-Tai Chen and Yu-Chie Chen* A Two-Matrix System for MALDI MS Analysis of Serine Phosphorylated Peptides Concentrated by Fe3O4@Al2O3 Magnetic Nanoparticles. J. Mass Spectrom. 2008, 43,  538-541.

51.  Cheng-Tai Chen and Yu-Chie Chen* Trapping Performance of Fe3O4@Al2O3 and Fe3O4@TiO2 Magnetic Nanoparticles in the Selective Enrichment of Phosphopeptides from Human Serum. J. Biomed. Nanotechnol. 2008,  4, 73–79.

50. Wei-Chieh Huang and Yu-Chie Chen* Photochemical Synthesis of Polygonal Gold Nanoparticles. J. Nanopart. Res. 2008, 10, 697-702.

49.  Wei-Jen Chen, Pei-Jane Tsai, Yu-Chie Chen*  Functional Fe3O4/TiO2 Core/Shell Magnetic Nanoparticles as the Photo-Killing Agents for Pathogenic Bacteria. Small. 2008, 4, 485–491.

48. Chun-Yuan Lo, Jia-Yi Lin, Wei-Yu Chen, Cheng-Tai Chen, Yu-Chie Chen* Surface-assisted Laser Desorption/Ionization mass spectrometry on titania nanotube arrays. J. Am. Soc. Mass Spectrom. 2008, 19, 1014-1020.

47. Jr-Chi Liu, Pei-Jane Tsai, Yuan C. Lee, Yu-Chie Chen* Affinity Capture of Uropathogenic E. coli Using Pigeon Ovalbumin-Bound Fe3O4@Al2O3 Magnetic Nanoparticles. Anal. Chem. 2008, 80, 5425-5432.

46. Wei-Jen Chen, Pei-Jane Tsai, Yu-Chie Chen* Functional Nanoparticle-Based Proteomic Strategies for Rapid Characterization of Pathogenic Bacteria. Anal. Chem. 2008, 80 , 9612–9621.

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2007 

45. Wei-Chieh Huang, Pei-Jane Tsai, Yu-Chie Chen* Functional Gold Nanoparticles as the Photothermal Agents for Selective Killing of Pathogenic Bacteria. Nanomedicine. 2007, 2, 777-787.

44. Yi-Cheng Li, Ya-Shiuan Lin, Pei-Jane Tsai, Cheng-Tai Chen, Wei-Yu Chen, Yu-Chie Chen*  Nitrilotriacetic Acid-Coated Magnetic Nanoparticles as Affinity Probes for Enrichment of Histidine-Tagged Proteins and Phosphorylated Peptides. Anal. Chem. 2007, 79, 7519-7525.

43. Chun-Yuen Lo, Wei-Yu Chen, Cheng-Tai Chen, Yu-Chie Chen* Rapid Enrichment of Phosphopeptides from Peptide Mixtures Using Iron Oxide Nano-composites of Magnetic Particles Coated with Zirconia as the Concentrating Probes. J. Proteome Res. 2007, 6, 887-893 .

42. Cheng-Tai Chen, Wei-Yu Chen, Pei-Jane Tsai, Kun-Yi Chien, Jau-Song Yu, and Yu-Chie Chen* Rapid Enrichment of Phosphopeptides and Phosphoproteins from Complex Samples Using Magnetic Particles Coated with Alumina as the Concentrating Probes for MALDI MS Analysis. J. Proteome Res. 2007, 6, 316-325.

41. Wei-Yu Chen and Yu-Chie Chen*Acceleration of Microwave-Assisted Enzymatic Digestion Reactions by Magnetite Beads. Anal. Chem. 2007, 79, 2394-2401.

40. Wei-Yu Chen and Yu-Chie Chen*MALDI MS Analysis of Oligonucleotides: Desalting by Functional Magnetite Beads Using Microwave-assisted Extraction. Anal. Chem. 2007, 79, 8061-8066.

39. Chilap Kuong, Wei-Yu Chen, Yu-Chie Chen* Semi-quantitative Determination of Cationic Surfactants in Aqueous Solutions Using Gold Nanoparticles as Reporter Probes. Anal. Bioanal. Chem. 2007, 387, 2091-2099.

38. Chen-Yu Hong and Yu-Chie Chen* Selective Enrichment of Ochratoxin A Using Human Serum Albumin Immobilized Magnetic Beads as the Concentrating Probes for Capillary Electrophoresis/Electrospray Ionization Mass Spectrometric Analysis. J. Chromatogr. A, 2007, 1159, 250-255.

37. Wei-In Hsiao, Ya-Shiuan Lin, Yu-Chie Chen,* Chi-Shen Lee*The effect of nanocrystalline CeO2 on ethanol reforming. Chem. Phys. Lett. 2007, 441,  294-299.  

36. Tai-Chia Chiu, Li-Shing Huang, Po-Chiao Lin, Yu-Chie Chen,* Yu-Ju Chen,* Chun-Cheng Lin, and Huan-Tsung Chang* Nanomaterial Based Affinity Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Biomolecules and Pathogens. Recent Patents on Nanotechnology. 2007, 1, 99-111.

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2006

35. Hong-Yi Lin, Cheng-Tai Chen, Yu-Chie Chen* Detection of Phosphopeptides by Localized Surface Plasma Resonance of Titania Coated Gold Nanoparticles Immobilized on Glass Substrates. Anal. Chem. 2006, 78, 6873-6878.

34. Wei-Yu Chen and Yu-Chie Chen* Affinity Based Mass Spectrometry by Using Iron Oxide Magnetic Particles as the Matrix and Concentrating Probes for SALDI MS Analysis of Peptides and Proteins. Anal. Bioanal. Chem. 2006, 386, 699-704.

33. Yi-Ting Wu and Yu-Chie Chen* Determination of Calcium in Complex Samples Using Functional Magnetic Beads Combined with Electrodeless/Sheathless Electrospray Ionization Mass Spectrometry. Rapid Commun. Mass Spectrom. 2006, 20, 1995-1999 .

32. Huei-Hsuan Cheng, Szu-Heng Liu, Hui-Cheng Lee, Ya-Shiuan Lin, Zu-Han Huang, Cheng-I Hsu, Yu-Chie Chen, Yen-Chung Chang* The heavy chain of cytoplasmic dynein is a major protein component of the postsynaptic density fraction. J. Neurosci. Res. 2006, 84, 244-254.

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2005

31. Cheng-Tai Chen and Yu-Chie Chen* Fe3O4/TiO2 Core/Shell Nanoparticles as Affinity Probes for the Analysis of Phosphopeptides Using TiO2 Surface-Assisted Laser Desorption/Ionization Mass Spectrometry. Anal. Chem. 2005, 77, 5912-5919.

30. Hun-Yun Chen and Yu-Chie Chen* Characterization of Intact Penicillium Spores by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.  Rapid Commun. Mass Spectrom. 2005, 19, 3564-3568.

29. Yi-Ting Wu and Yu-Chie Chen* Sheathless Capillary Electrophoresis/ Electrospray Ionization Mass Spectrometry Using a Pulled Bare Fused-Silica Capillary as the Electrospray Emitter. Anal. Chem. 2005, 77, 2071-2077. 

28. Ya-Shiuan Lin, Pei-Jane Tsai, Mao-Feng Weng, Yu-Chie Chen* Affinity Capture Using Vancomycin-bound Magnetic Nanoparticles for the MALDI-MS Analysis of Bacteria. Anal Chem. 2005, 77, 1753-1760.

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2004

27. Ya-Shiuan Lin, Chin-Hsiung Yang, Yu-Chie Chen* Glass-Chip-Based Sample Preparation and On-Chip Tryptic Digestion for MALDI Mass Spectrometric Analysis using a sol-gel-DHB Hybrid Matrix. Rapid Commun. Mass Spectrom. 2004, 18, 313- 318.

26. Cheng-Tai Chen and Yu-Chie Chen* Molecularly Imprinted TiO2-Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry for Selectively Detecting a-Cyclodextrin. Anal. Chem. 2004, 76, 1453 - 1457.

25. Mao-Feng Weng and Yu-Chie Chen* Using Sol–Gel/Crown Ether Hybrid Materials as a Desalting Substrate for MALDI Analysis of Oligonucleotides. Rapid Commun. Mass Spectrom. 2004, 18, 1421-1428.

24. Chien-Hsun Teng, Kun-Chan Ho, Ya-Shiuan Lin, Yu-Chie Chen* Gold Nanoparticles as Selective and Concentrating Probes for Samples in MALDI MS Analysis. Anal. Chem. 2004, 76, 4337-4342.

23. Cheng-Tai Chen and Yu-Chie Chen* Desorption/Ionization Mass Spectrometry on Nanocrystalline Titania Sol–Gel-Deposited Films. Rapid Commun. Mass Spectrom. 2004, 18, 1956-1964 .

22. Wei-Yu Chen, Lung-Shen Wang, Hsin-Tien Chiu, Yu-Chie Chen*, Chi-Young Lee. Carbon Nanotubes as Affinity Probes for Peptides and Proteins in MALDI MS Analysis. J. Am. Soc. Mass Spectrom. 2004, 15, 1629-1635.

21. Kun-Chan Ho, Pei-Jane Tsai, Ya-Shiuan Lin, Yu-Chie Chen* Using Biofunctionalized Nanoparticles to Probe Pathogenic Bacteria. Anal. Chem. 2004, 76, 7162-7168 (accelerated article).

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2003

20. Chien-Hsun Teng and Yu-Chie Chen* Fiber Introduction Mass Spectrometry: Coupling Solid-Phase Microextraction with Sol-gel Assisted Laser Desorption/ionization Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom. 2003, 17, 1092-1094.

19. Wei-Yu Chen and Yu-Chie Chen* Reducing Alkali Cation Adductions of Oligonucleotides Using Sol-gel Assisted Laser Desorption /ionization Mass Spectrometry. Anal. Chem. 2003, 75, 4223-4228.

18. Kun-Chan Ho, Ya-Shiuan Lin, Yu-Chie Chen* Laser Desorption/ionization Mass Spectrometry on Various Sol-Gel-Derived Dihydroxybenzoic Acid Isomeric Films. Rapid Commun. Mass Spectrom. 2003, 17, 2683-2687.

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2002

17. Ya-Shiuan Lin and Yu-Chie Chen* Laser Desorption/ Ionization Time-of-Flight Mass Spectrometry on Sol-Gel-Derived 2, 5-Dihydroxybenzoic Acid Film. Anal. Chem. 2002, 74, 5793-5798.

16. Jia-Yi Wu and Yu-Chie Chen* A Novel Approach by Combining Thin Layer Chromatography with Surface-assisted Laser Desorption / Ionization (SALDI) Time-of-Flight Mass Spectrometry. J. Mass Spectrom. 2002, 37, 85-90.

15. Yu-Chie Chen*, Tzu-Ying Li, Ming-Fei Tsai. Analysis of the Saliva from Patients with Oral Cancer by Matrix-assisted Laser Desorption/ Ionization Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom. 2002, 16, 364-369.

14. Yu-Chie Chen* and Mei-Chuan Sun. Qualitative Determination of Trace Quantities of Nonyl-Phenyl Polyethylene Glycol Ether in Water Based on Solid Phase Microextraction Combined with Surface-Assisted Laser Desorption/Ionization (SALDI) Mass Spectrometry. Rapid Commun. Mass Spectrom. 2002, 16, 1243-1247.

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2001

13. Yu-Chie Chen,* Jia-Yi Wu. Analysis of Small Organics on Planar Silica Surfaces Using Laser Desorption Mass Spectrometry. Rapid Commun. Mass Spectrom. 2001, 15, 1899-1903.

12. Yu-Chie Chen,* Mei-Chuan Sun. Determination of Trace Quaternary Ammonium Surfactants in Water by Combining Solid Phase Extraction (SPE) with Surface-assisted Laser Desorption/ Ionization (SALDI) Mass Spectrometry. Rapid Commun. Mass Spectrom. 2001, 15, 2521-2525.

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Before 2001

11. Yu-Chie Chen,* Jentaie Shiea, Jan Sunner  Rapid Determination of Trace Nitrophenolic Organics in Water by Combining Solid Phase Extraction with Surface-Assisted Laser Desorption Ionization (SALDI) /Time-of-Flight Mass Spectrometry, Rapid Commun. Mass Spectrom. 2000, 14, 86-90.

10. Yu-Chie Chen,* Ming-Fei Tsai  Using Surfactants to Enhance the Analyte Signals in Activated Carbon, Surface-assisted Laser Desorption Ionization (SALDI) Mass Spectrometry. J. Mass Spectrom. 2000, 35, 1278-1284.

9. Yu-Chie Chen,* Ming-Fei Tsai Sensitivity Enhancement for Nitrophenols Using Cationic Surfactant-Modified Activated Carbon for Solid Phase Extraction (SPE)/ Surface-assisted Laser Desorption Ionization (SALDI) Mass Spectrometry. Rapid Commun. Mass Spectrom. 2000, 14, 2300-2304.

8. Tzu-Ying Li, Biing-Hui Liu, Yu-Chie Chen* Characterization of Aspergillus Spores by Matrix-assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom. 2000, 14, 2393-2400.

　

7. Yu-Chie Chen* In Situ Determination of Organic Reaction Products by Combining Thin Layer Chromatography with Surface-assisted Laser Desorption Ionization (SALDI) /Time-of-Flight Mass Spectrometry. Rapid Commun. Mass Spectrom.1999, 13, 821-825.

　

6. Jen-Pang Huang, Cheng-Hui Yuan, Jentaie Shiea, Yu-Chie Chen* Rapid Screening for Diuretic Doping Agents in Urine by C60-assisted Laser Desorption Ionization/time of Flight Mass Spectrometry. J. Anal. Toxicol. 1999, 23, 337-342.
　
5. Yu-Chie Chen,* Anren Hu. Simultaneous Determination of Trace Benzodiazepines from Drinks by Using Direct Electrospray Probe/Mass Spectrometry (DEP/MS). Forensic Sci. Int. 1999, 103, 79-88.

　

4.  Yu-Chie Chen, Jentaie Shiea, Jan Sunner* Mass Spectrometry/Thin Layer

Chromatography using Activated Carbon, Surface Assisted Laser

Desorption/Ionization, J. Chromatogr. A, 1998, 826, 77-86

　

3. Yu-Chie Chen, Hsing-Long Chei, Jentaie Shiea*   Analysis of Gaseous

Ammonia, Volatile Primary Amines and Quaternary Ammonium Salts at

Subambinent Temperature by Liquid Secondary Ion Mass Spectrometry, J.

Mass Spectrom., 1996, 31, 464-471.

　

2. Yu-Chie Chen; Jentaie Shiea* Selective Enhancement of Ion Signal of      Charged Surfactant in Fast Atom Bombardment. J. Mass Spectrom., 1995, 30, 1435-1440.

 

1. Jan Sunner,* Edwards Dratz, Yu-Chie Chen. Graphite Surface Assisted     Laser Desorption/Ionization Time of Flight Mass Spectrometry of Peptides and Proteins from Liquid Solutions, Anal. Chem., 1995, 67, 4335-4342.

* Corresponding author

Book

1. Pawel L. Urban, Yu-Chie Chen, Yi-Sheng Wang.  Time-Resolved Mass Spectrometry: From Concept to Applications. 2016, Wiley (ISBN: 978-1-118-88732-5).

 

 

Patents

 1. Yu-Chie Chen, Cheng-Tai Chen and Ya-Shiuan Lin. Metal oxide-assisted laser desorption/ionization mass spectrometry. US Patent no.: US7122792B2.

 2. Yu-Chie Chen, Cheng-Tai Chen and Ya-Shiuan Lin. Metal oxide-assisted laser desorption/ionization mass spectrometry. ROC Patent no.: I 274874.

3. Yu-Chie Chen and Wei-Chieh Huang, Functional nanoparticle-based antibiotics. ROC Patent no.: I 389695.

4. Yu-Chie Chen, Cheng-Tai Chen, Ya-Shiuan Lin, Hong-Yi Lin, Chun-Yuan Lo, Metal oxide nano-composite magnetic materials, their fabrication methods and applications in linkage, enrichment, and isolation of phosphorylated species. US Patent no.: US 8735176 B2.